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Medical Literature Library

In addition to great our medical education resources, we also offer these articles and blogs for your reference. If there is anything specific you would like to learn about, let us know today by contacting our Medical Affairs team.

Topical Application of Skin Biome Care Regimen Containing Live Cultures and Ferments of Cutibacterium acnes defendens strain XYCM42 and the Impact on Clinical Outcomes Following Microneedle-induced Skin Remodeling

The skin, our body's largest organ, hosts a complex microbiome that plays a pivotal role in maintaining health and protecting against pathogens. Even slight disruptions to this delicate balance can influence skin health and disease. Among the diverse microbial community, Cutibacterium acnes (C. acnes) subspecies defendens is known for its positive contirbution to skin health. Hoewver, interaction between living microbe probiotics and would healing after aesthetic procedures, such as microneedling, remains unexplored.

4 Top Misconceptions About Skin Probiotics

Beauty trends come and go, and many companies are attempting to hop on the biome bandwagon, with consumers' demand rising. But when it comes to the subject of the skin biome (the ecosystem of the skin, including the skin microbiome), there is a lot of noise out there that can be confusing or even misleading. And when it comes to skin, legitimate skin-relevant probiotic strains of bacteria are worth the hype despite the many persistent misconceptions and skin care myths. ARTICLE PUBLISHED IN SKIN INC.

Understanding C. acnes: It’s Not the Villain You Think It Is

For a long time, the bacterial species Cutibacterium acnes (also known as C. acnes) has been blamed as the cause of acne. However, recent studies have shown that not all strains of this microbe are harmful. In fact, some strains can be highly beneficial, making it essential to have these health-related strains on our skin. It is important to consider what other microbes are involved and how the skin and immune system respond to the presence of all these microbes and their metabolites.

The Truth About Microbes

So, what is the human microbiota, and what does the general public need to know about it? This article will focus on the nature of the skin microbiome and its constituents and endeavor to clear up some common misconceptions about it. The skin biome encompasses all living actors on the skin, including the skin cells themselves, while the skin microbiome includes the microbes that populate the skin biome.

Why a Healthy Microbiome Is Better Than Any Skincare Product

While no one particularly relishes the idea of millions of microorganisms crawling around, the truth is that much of our skin health is determined by our microbiome. The skin microbiome is made up of healthy skin bacteria and fungi, and it’s our largest organ’s natural defense system. When the skin biome is thriving, our bodies are healthier, our bones and musculature are safe, and our skin is hydrated and glowing. ARTICLE PUBLISHED IN ELEPHANT JOURNAL

Understanding the Faceted Nature of the Cutibacterium acnes Species

When we talk about probiotics, we often refer to what species or number of species are contained in that probiotic product. But did you know that not all microbes within a species are the same? Significant differences between strains of a species are a common phenomenon and is the case with the bacteria species Cutibacterium acnes. This species lives on everyone's skin, but many strains have different characteristics.

Understanding Microbiome Diversity: Is It the Secret to Better Health?

It has been said that “Variety is the very spice of life” — a sentiment that diversity often makes things more interesting, sometimes better. The same is said to be true when it comes to the microbes that live in and on our bodies, namely our microbiomes. Skin microbiome diversity has become more of a focus in recent years, and alpha and beta diversity are two metrics used to look at microbiome diversity.

Why Some C. acnes Bacteria are Vital for Skin Health

Although the general public typically blames the species of bacteria named C. acnes (formally referred to as P. acnes) for acne breakouts, the truth is a bit more complicated. The presence of C. acnes strains on the skin certainly correlates with acne cases, but they aren’t necessarily responsible for the occurrence of acne (correlation vs. causation). ARTICLE PUBLISHED IN SKIN, INC.

How to Restore the Skin’s Microbiome from Over-Sanitizing

Measures used to prevent the spread of viruses, such as increased frequency of hand washing and the use of hand sanitizers, are likely helpful in slowing the spread of illnesses. However, that frequency of use also has a significant impact on the skin barrier and the skin biomes, potentially causing dysbiosis, which can lead to undesirable skin issues. In this article, we’ll unpack the causes of each of these issues, as well as how to help restore the skin biome when such issues arise. ARTICLE PUBLISHED IN MED CITY NEWS

Is XYCM42 the Future of Probiotic Skin Care?

Recent research shows that a strain of C. acnes defendens—dubbed XYCM42—might be the leading candidate for a legitimate skin probiotic. What does that mean for skin care/skin biome innovation? ARTICLE PUBLISHED IN GLOBAL COSMETIC INDUSTRY

What You Need to Know About the Skin’s Microbiome

The skin’s microbiome is the community of microbes — such as bacteria, fungi, and other microorganisms. Although some of these microbes can be problematic at times, many of them are essential for immune system health, protection from pathogens, and other critical functions. Healthy skin bacteria, such as probiotics, can help.

The Benefits of Microneedling for Acne Scars and Wrinkles

A major trend in skin care, the benefits of microneedling for acne scars and wrinkles are immense — and the science backs up these claims.

Removing the Barriers for Translation of Skin Microbiome Science into Real World Applications

The topic of the skin microbiome has captured the attention of the medical community, yet there has been minimal progress in translating all of the latest scientific knowledge of the subject into actionable therapeutic options - until now. ARTICLE PUBLISHED IN MODERN AESTHETICS AND PRACTICAL DERMATOLOGY

Rethinking skin probiotics: Replenishing lost skin commensals could be key to keeping skin looking younger, longer

Anyone who has their eye on the skincare market can tell you that the terms “microbiome” and “probiotic” have not only entered the common skincare vernacular, but are expected from most consumer brands. ARTICLE PUBLISHED IN MODERN AESTHETICS AND PRACTICAL DERMATOLOGY

Rebooting the C. acnes Narrative

As a skin scientist, I find it fascinating that there is so much attention these days on the skin microbiome. One of the biggest misconceptions when it comes to the microbiome in general is that all microbes within a given species are the same. They aren't. LETTER TO THE EDITOR PUBLISHED IN PRACTICAL DERMATOLOGY